| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219185 | Tetrahedron | 2012 | 11 Pages |
Abstract
The reaction of arynes, generated from ortho-(trimethylsilyl)aryl triflates, with the CO bond of formamides gave salicylaldehyde derivatives via the formation of formal [2+2] adducts. The sequential transformation of arynes into ortho-disubstituted arenes, o-aminoalkylphenols or o-hydroxyalkylphenols, was achieved by one-pot procedure using dialkylzincs.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eito Yoshioka, Hideto Miyabe,