Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219187 | Tetrahedron | 2012 | 7 Pages |
Abstract
A library of hybrid oxazole-triazole based compounds containing contiguously linked aromatic units were synthesised as G-quadruplex binding ligands. The design of these ligands was based upon combining features of our first generation of G-quadruplex bis-triazole ligands and the natural product telomestatin. The syntheses and biophysical studies of these ligands are described.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dougal J. Ritson, John E. Moses,