| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219189 | Tetrahedron | 2012 | 6 Pages |
Abstract
‘One-pot’ tandem reactions of commercially available 1,4-dithiane-2,5-diol (the dimer of mercaptoacetaldehyde) with electrophilic alkenes resulted in the facile formation of substituted tetrahydrothiophene derivatives. Thus, sulfa-Michael/Henry and sulfa-Michael/aldol sequences provided polysubstituted tetrahydrothiophenes using in situ generated nitroalkenes and α,β-unsaturated carbonyl compounds as the electrophilic partners of mercaptoacetaldehyde dimer, respectively.
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