Article ID Journal Published Year Pages File Type
5219227 Tetrahedron 2012 5 Pages PDF
Abstract

A new protocol for the synthesis of polysubstituted isocoumarins from 2-iodobenzoic acid and β-diketone compounds has been developed. The occurrence of C-arylation cyclization reaction in transition-metal-free systems and ortho-induced substrates has been exploited. Reactions using these inexpensive conditions have displayed high functional group tolerance and excellent yields.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry