| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219241 | Tetrahedron | 2012 | 8 Pages |
Abstract
A modified traditional preparative chromatographic column can be used to achieve quantitative N-dearylation of N-(alkoxyphenyl), N-(alkoxynaphthyl), and N-(alkoxybenzyl)-2-azetidinones under mild conditions. Starting materials are charged on top of the column and the pure N-unsubstituted 2-azetidinones leave the column minutes later without need for other purifications. The yields are good-to-excellent and the reaction condition is mild, easy, efficient, and cheap.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
