Article ID Journal Published Year Pages File Type
5219307 Tetrahedron 2012 8 Pages PDF
Abstract

An efficient one-pot sequential intermolecular aza-Michael addition and Pd-catalyzed intramolecular Buchwald-Hartwig α-arylation of secondary amines have been investigated, for the synthesis of tetrahydroisoquinolines. This method is simple and furnished products in very good yield and also successfully applied for the synthesis of novel aza-spirotricylcic ethers.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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