Article ID Journal Published Year Pages File Type
5219334 Tetrahedron 2011 8 Pages PDF
Abstract

An efficient method for the stereoselective synthesis of 3-(diarylmethylene)-2-oxindoles and 3-(arylmethylene)-2-oxindoles via carbopalladation is described. In this approach, an Ugi-4-component reaction (4-CR) adduct was used as the starting material. A one-pot sequence involving intermolecular carbopalladation C–H activation/C–C bond formation efficiently afforded the oxindole derivatives.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry