| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219366 | Tetrahedron | 2012 | 9 Pages |
Simple, very efficient, and having some aspects of generality, synthesis of water-soluble, polyanionic dendrimeric polyesters with different size, polarity, and flexibility is described. These macromolecular compounds consisting of phosphate or thiophosphate ester units and 1,3,5-benzenetricarboxylic acid building blocks may find potential applications as pharmaceutical agents. Synthesized the title polyanionic dendrimers possess charged carboxyl functional groups on the surface and were obtained, in high yields, from previously prepared series of new phosphorus-based dendrimeric polyols. The key monomers applied in this project were 1,3,5-benzenetricarboxylic acid dibenzyl ester and 1,3,5-benzenetricarboxylic acid bis(4-methoxybenzyl) ester. Both worked as the essential precursors of the dendrimer polyanionic surface.
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