| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219470 | Tetrahedron | 2012 | 9 Pages |
Abstract
Selective amine de-alkylation enables the conversion of Sommelet-Hauser rearrangement products into 2-aryl-2-bromoacetic acid derivatives. These compounds are valuable synthetic intermediates in the synthesis of α-aryl-α-amino or α-aryl-β-amino acid derivatives. The method presented herein is a formal de-N,N-dialkylation of Sommelet-Hauser rearrangement products.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eiji Tayama, Ryota Sato, Keisuke Takedachi, Hajime Iwamoto, Eietsu Hasegawa,