| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219473 | Tetrahedron | 2012 | 5 Pages |
Abstract
A novel series of β-lactams bearing an anthraquinone moiety have been synthesized from imines derived from anthraquinone-2-carbaldehyde and ketenes by a [2+2] cycloaddition reaction. The cycloadducts were fully characterized and evaluated for their antimalarial activities against Plasmodium falciparum K14 resistant strain and showed moderate to excellent EC50 values varying from 9 to 50 μM.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Aliasghar Jarrahpour, Edris Ebrahimi, Reza Khalifeh, Hashem Sharghi, Mohammad Sahraei, Véronique Sinou, Christine Latour, Jean Michel Brunel,