| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219481 | Tetrahedron | 2012 | 8 Pages |
Abstract
Catalytic intramolecular additions of hydroxyl groups to tethered conjugated dienes are described. The reactions proceed smoothly at 60 °C in the presence of 5 mol % of (PPh3)AuCl/AgOTf as a catalyst. A broad range of structurally diverse conjugated dienes produce substituted tetrahydrofurans and tetrahydropyrans in good yields. This reaction represents an atom-economic route to construct five- and six-membered cyclic ethers.
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