Article ID Journal Published Year Pages File Type
5219492 Tetrahedron 2012 7 Pages PDF
Abstract

4-(N,N-dimethylamino)pyridine (DMAP) was found to be a fairly efficient catalyst for the Morita–Baylis–Hillman reactions of isatins with α-substituted allenoates to give the corresponding products in good to high yields with moderate diastereoselectivities under mild conditions.

Graphical abstract4-(N,N-dimethylamino)pyridine (DMAP)-catalyzed Morita–Baylis–Hillman (MBH) reaction of isatins with α-substituted allenoates has been investigated. This reaction can afford the corresponding MBH products in good to high yields with moderate diastereoselectivities under mild conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry