Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219492 | Tetrahedron | 2012 | 7 Pages |
Abstract
4-(N,N-dimethylamino)pyridine (DMAP) was found to be a fairly efficient catalyst for the Morita–Baylis–Hillman reactions of isatins with α-substituted allenoates to give the corresponding products in good to high yields with moderate diastereoselectivities under mild conditions.
Graphical abstract4-(N,N-dimethylamino)pyridine (DMAP)-catalyzed Morita–Baylis–Hillman (MBH) reaction of isatins with α-substituted allenoates has been investigated. This reaction can afford the corresponding MBH products in good to high yields with moderate diastereoselectivities under mild conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide
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