Article ID Journal Published Year Pages File Type
5219570 Tetrahedron 2012 7 Pages PDF
Abstract

We described herein the use of selenium compounds in Click Chemistry by copper catalyzed 1,3-dipolar cycloaddition of azidomethyl arylselenides with alkynes. The reactions were performed under mild conditions reacting azidomethyl arylselenides with a range of terminal alkynes using catalytic amount of Cu(OAc)2.H2O/sodium ascorbate and the corresponding 1-(arylseleno-methyl)-1,2,3-triazoles were obtained in high yields. The reaction time of these reactions could be reduced to a few minutes using microwave irradiation.

Graphical abstractDownload full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , ,