Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219570 | Tetrahedron | 2012 | 7 Pages |
Abstract
We described herein the use of selenium compounds in Click Chemistry by copper catalyzed 1,3-dipolar cycloaddition of azidomethyl arylselenides with alkynes. The reactions were performed under mild conditions reacting azidomethyl arylselenides with a range of terminal alkynes using catalytic amount of Cu(OAc)2.H2O/sodium ascorbate and the corresponding 1-(arylseleno-methyl)-1,2,3-triazoles were obtained in high yields. The reaction time of these reactions could be reduced to a few minutes using microwave irradiation.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Natália Seus, Maiara T. Saraiva, Eduardo E. Alberto, Lucielli Savegnago, Diego Alves,