Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219591 | Tetrahedron | 2012 | 6 Pages |
Abstract
Water soluble cationic diselenide derivatives of benzimidazolin-2-selenones and imidazolin-2-selenones have been synthesized. The Glutathione Peroxidase-like (GPx-like) activities of cationic diselenides have been investigated for the first time. The GPx-like activities are found to be quite low as compared to the neutral imidazole based diselenide and intramolecularly coordinated diselenides. A mechanism for GPx-like activity has been proposed. The oxidation reactions of N-heterocyclic carbene derived selenones with hydrogen peroxide have been studied.
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