Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219644 | Tetrahedron | 2011 | 5 Pages |
Abstract
The use of zinc salts as cocatalysts in aldol condensations catalyzed by single prolinamide (and in the extension by other more complex prolinamides) can prevent the formation of the parasitic intermediate imidazolidinone, with faster and also more stereoselective reactions than those catalyzed by the free amine. This new finding, together with this ion's already known properties, make zinc salts highly suitable additives for aldol reactions catalyzed for prolinamide derivatives.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Cecilia Andreu, Teresa Varea, Gregorio Asensio,