| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219658 | Tetrahedron | 2011 | 11 Pages |
Abstract
A radical addition reaction promoted by Na2S2O4 of perfluoroalkyl iodides with 2,3-allenols affording E/Z mixtures of 3-iodo-4-perfluoroalkyl-substituted allylic alcohols has been studied. Kinetic resolution with Sonogashira coupling reaction was applied to afford the Z isomer of 3-iodo-4-perfluoroalkyl-substituted allylic alcohol (Z-3) and the E isomer of conjugated enynic diols (E-5) in 39-52% and 22-40% yields, respectively.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhichao Ma, Rong Zeng, Chunling Fu, Shengming Ma,