Article ID Journal Published Year Pages File Type
5219670 Tetrahedron 2012 5 Pages PDF
Abstract

Bidentate phosphine ligands in palladium-catalyzed intramolecular Heck reactions of 2-chloroquinolin-3-yl-(1-homoallyl)alcohols are described to afford facile synthesis of 3-methylene-2,3-dihydro-1H-cyclopenta[b]quinolines in improved yields. We further observed using bulky aromatic phosphine ligand in Pd-catalyzed intermolecular Heck coupling reaction at olefinic centers with iodobenzene also favored exclusively Heck products in excellent yield.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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