Article ID Journal Published Year Pages File Type
5219671 Tetrahedron 2012 7 Pages PDF
Abstract

The design and synthesis of derivatives of 4-hydroxy-Tamoxifen as potential antagonists of the nuclear receptor LRH-1 are described. Stereoselective McMurry coupling was used to generate the desired internal alkene and a novel method for the synthesis of tetrasubstituted cyclopropane analogues was also developed.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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