Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219683 | Tetrahedron | 2012 | 4 Pages |
Abstract
A synthetic approach for the total synthesis of salinipyrone A has been developed. Key steps involve the TiCl4-mediated vinylogous Mukaiyama aldol reaction (VMAR) of chiral ketene silyl N,O-acetal with propionaldyhyde, an aldol condensation, Witting olefination, and a cyclization. The synthesis proceeds in eight steps.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Palakuri Ramesh, Harshadas Mitaram Meshram,