| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219738 | Tetrahedron | 2012 | 7 Pages |
Abstract
Nine new steroids, sclerosteroids A-I (1, 5, 6, 8-13), along with 18 known metabolites (2-4, 7, 14-27), were isolated from the soft coral Scleronephthya gracillimum. These structures were elucidated on the basis of detailed spectroscopic analysis. The absolute configurations of sugar moieties in steroidal glycosides 10-13 were determined by HPLC analysis of the o-tolylthiocarbamate derivatives of the liberated sugars from hydrolysis of these steroidal giycosides. Cytotoxic and anti-inflammatory activities of these compounds were measured in vitro.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hui-Yu Fang, Chih-Chuang Liaw, Chih-Hua Chao, Zhi-Hong Wen, Yang-Chang Wu, Chi-Hsin Hsu, Chang-Feng Dai, Jyh-Horng Sheu,