Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219753 | Tetrahedron | 2012 | 8 Pages |
Abstract
Markovnikov-type hydroiodination of terminal alkynes with iodine and Ph2P(O)H took place selectively to afford the corresponding internal iodoalkenes in good yields. Combination of (PhO)2P(O)H and Ph2P(O)OH instead of Ph2P(O)H also provided internal iodoalkenes in excellent yields. This hydroiodination is advantageous in terms of mild conditions, convenient operation, and tolerance to various functional groups. In addition, direct synthesis of internal iodoalkenes from silylalkynes was also achieved by using a mixed system of iodine and phosphorus reagents.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shin-ichi Kawaguchi, Haruna Masuno, Motohiro Sonoda, Akihiro Nomoto, Akiya Ogawa,