| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219787 | Tetrahedron | 2011 | 9 Pages |
Abstract
The iodination of chlorinated aromatic compounds using Ag2SO4/I2, AgSbF6/I2, AgBF4/I2, and AgPF6/I2 offers access to iodoarenes that are valuable intermediates in organic synthesis. Specifically, iodination of phenols, anisoles, and anilines with a 3,5-dichloro substitution pattern preferentially yielded the ortho, para, and para iodinated product, respectively. In the case of chlorobenzene and 3-chlorotoluene, AgSbF6/I2, AgBF4/I2, and AgPF6/I2, but not Ag2SO4/I2, selectively introduced the iodine in para position to the chlorine substituent.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
