Article ID Journal Published Year Pages File Type
5219789 Tetrahedron 2011 6 Pages PDF
Abstract

An efficient method for enantioselective synthesis of β-nitrophosphonates via the Michael addition of diphenyl phosphite to nitroalkenes using the readily available quinidine thiourea organocatalyst has been developed. The desired β-nitrophosphonates were obtained in good ee values. Molecular sieves were found to be crucial for achieving high reproducible yields in this reaction.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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