Article ID Journal Published Year Pages File Type
5219800 Tetrahedron 2011 6 Pages PDF
Abstract

A high yielding, simple, and flexible copper-based system for N-arylation of fluorinated sulfoximines is reported. Best results were achieved using copper iodide in combination with DMEDA and Cs2CO3 to provide a wide range of N-arylated perfluoroalkylated sulfoximines. These conditions tolerate a great number of substituents on either aromatic cycle, including heteroaromatic rings, for the N-functionalization.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry