Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219832 | Tetrahedron | 2012 | 6 Pages |
Abstract
Five new polyketides including two benzopyranones (1 and 2), one isochroman (3) and two anthraquinone-citrinin derivatives (4 and 5) were isolated from the sea fan-derived fungus Penicillium citrinum PSU-F51 together with thirteen known compounds. The structures were determined by spectroscopic methods. The anthraquinone-citrinin derivatives are rare natural products. Compound 4 displayed moderate antibacterial activity against both Staphylococcus aureus and methicillin-resistant S. aureus with equal MIC values of 16 μg/mL, while the known coniochaetone A displayed moderate antifungal activity against Candida albicans with MIC value of 16 μg/mL.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nanthaphong Khamthong, Vatcharin Rukachaisirikul, Souwalak Phongpaichit, Sita Preedanon, Jariya Sakayaroj,