β-Lactam-synthon-interceded diastereoselective synthesis of functionally enriched thioxo-imidazolidines, imidazolidin-2-ones, piperazine-5,6-diones and 4,5-dihydroimidazoles

The manuscript explicates simple and convenient protocols for the diastereoselective synthesis of functionally decorated thioxo-imidazolidines, imidazolidin-2-ones, piperazine-5,6-diones and 4,5-dihydroimidazoles using β-lactam synthon approach with an extension towards one-pot synthesis. Since the developed methodology does not employ either the use of Lewis acid conditions or Pd-catalyzed customary procedures, the developed route can be easily modulated for the synthesis of functionalized imidazoles with acid-sensitive functionalities and do not suffer from typical intricacies associated with conventional methods.

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