| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219934 | Tetrahedron | 2012 | 6 Pages |
Abstract
A sequence of two reactions: the Petasis reaction, in which an aminoacetaldehyde acetal was used as the amine component, followed by Pomeranz-Fritsch-Bobbitt cyclization, has been shown to be a convenient and simple method for the synthesis of tetrahydroisoquinoline-1-carboxylic acids. Using this method several acids have been prepared in good to excellent yields and characterized as hydrochloride salts.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maria Chrzanowska, Agnieszka Grajewska, Zofia Meissner, Maria Rozwadowska, Iwona Wiatrowska,