Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219939 | Tetrahedron | 2012 | 6 Pages |
Abstract
A highly efficient and environmental-benign oxidation by dioxygen (or air) as the sole oxidant was first applied for the conversion of 2-imidazoline-5-carboxylic derivatives to imidazole-5-carboxylic derivatives in very good and excellent yields. The substituent effect on 2-imidazoline ring was investigated. This protocol was also suitable for the synthesis of 2-imidazoles in relatively large scale.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yue Huang, Xiaodong Zu, Fan Wu, Jinyi Xu, Xiaoming Wu, Hequan Yao,