Article ID Journal Published Year Pages File Type
5219959 Tetrahedron 2011 4 Pages PDF
Abstract

A simple and efficient procedure was developed for the synthesis of multisubstituted 2-aminothiophene derivatives. In the presence of catalytic amount of imidazole, ketones or aldehydes, dicyanomethane and elemental sulfur were converted into the corresponding 2-aminothiophene derivatives in moderate to high yields in DMF at 60 °C.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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