| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5219966 | Tetrahedron | 2011 | 6 Pages |
Abstract
Nitrilotriacetic acid terminated tethers for trapping of His-tagged proteins have been synthesized and characterized. Compound 1, containing a lipophilic cholesterol anchor, hydrophilic oligoethoxy chain linker, and nitrilotriacetic acid terminus, can be used for attaching His-tagged proteins to phospholipid bilayers. Compound 2, containing a gold binding thioacetate anchor, hydrophilic oligoethoxy chain, and nitrilotriacetic acid terminus, can be used to tether His-tagged proteins to a gold surface.
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Related Topics
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Organic Chemistry
Authors
Ammathnadu S. Achalkumar, Richard J. Bushby, Stephen D. Evans,