Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5219979 | Tetrahedron | 2011 | 7 Pages |
Abstract
Fluorous organocatalyst 3 promotes direct asymmetric aldol reactions of ketones with aldehydes in brine, leading to the synthesis of the corresponding anti-aldol products in high yields with up to 96% ee. Fluorous organocatalyst 3 is easily recovered by solid-phase extraction using fluorous silica gel and can be reused up to five times without purification.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tsuyoshi Miura, Kie Imai, Hikaru Kasuga, Mariko Ina, Norihiro Tada, Nobuyuki Imai, Akichika Itoh,