Article ID Journal Published Year Pages File Type
5219979 Tetrahedron 2011 7 Pages PDF
Abstract

Fluorous organocatalyst 3 promotes direct asymmetric aldol reactions of ketones with aldehydes in brine, leading to the synthesis of the corresponding anti-aldol products in high yields with up to 96% ee. Fluorous organocatalyst 3 is easily recovered by solid-phase extraction using fluorous silica gel and can be reused up to five times without purification.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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