| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220069 | Tetrahedron | 2012 | 9 Pages |
Abstract
The palladium-catalyzed direct arylation at C2 or C5 of free NH2 substituted thiophene derivatives was found to proceed in moderate to high yields using a variety of aryl halides. The choice of potassium acetate as the base was found to be crucial to inhibit the amination reaction and to promote the direct arylation.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Fazia Derridj, Karima Si Larbi, Julien Roger, Safia Djebbar, Henri Doucet,