Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220095 | Tetrahedron | 2012 | 6 Pages |
Abstract
(S)-9-cis-4-Oxo-13,14-dihydroretinoic acid (S)-1, a new major endogenous vitamin A metabolite that activates retinoic acid receptor signaling both in vitro and in vivo, has been synthesized stereoselectively by Horner-Wadsworth-Emmons condensation and Stille cross-coupling as bond forming reactions.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marta DomÃnguez, Susana Álvarez, Rosana Álvarez, Ángel R. de Lera,