| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220174 | Tetrahedron | 2011 | 8 Pages |
Abstract
d-ribo-C18-phytosphingosine and l-arabino-C18-phytosphingosine were synthesised starting from commercially inexpensive d-fructose. Metal-mediated fragmentation and stereoselective reduction were used as key steps to provide the hydrophilic portion of d-ribo and l-arabino phytosphingosines. Grubbs' cross-metathesis and hydrogenation allowed the incorporation of hydrophobic tail.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ramu Sridhar Perali, Suresh Mandava, Sudharani Chalapala,