Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220301 | Tetrahedron | 2011 | 9 Pages |
Abstract
Axially chiral phosphine-oxazoline ligand L6 was found to be a fairly effective chiral ligand in silver(I)-catalyzed asymmetric Mannich reaction of N-Boc aldimines with trimethylsiloxyfuran to give the corresponding adducts in up to 97% yield, 7:1 dr and 86% ee (major diastereoisomer).
Graphical abstractAxially chiral phosphine-oxazoline ligand L6 was found to be a fairly effective chiral ligand in silver(I)-catalyzed asymmetric Mannich reaction of N-Boc aldimines with trimethylsiloxyfuran to give the corresponding adducts in up to 97% yield, 7:1 dr and 86% ee (major diastereoisomer).Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Qian-Yi Zhao, Min Shi,