| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220328 | Tetrahedron | 2011 | 7 Pages |
Abstract
A new series of Schiff bases derived from Cinchona alkaloids were developed as chiral ligands for the copper(II)-catalyzed asymmetric Henry reaction. The optimized catalyst can promote the Henry reaction of both aromatic and aliphatic aldehydes with nitromethane or nitroethane. Those reactions can afford the chiral β-nitro alcohol adducts with high enantioselectivities.
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Physical Sciences and Engineering
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Organic Chemistry
