| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220364 | Tetrahedron | 2012 | 6 Pages |
Abstract
The ring transformations of dichloro-β-lactam-fused 2-aryl-1,3-benzothiazines with sodium methoxide were investigated. With 2 equiv of base, the dichloro-β-lactam derivatives underwent rearrangement and dihydro-1,4-benzothiazepines, 3,4-substituted isoquinolines and substituted thiazole disulfides were isolated. A possible reaction mechanism is proposed for the simultaneous formation of the novel products. The formation of isoquinoline and thiazole derivatives can be explained by sulfur extrusion and addition sequences.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lajos Fodor, Péter Csomós, Antal Csámpai, Pál Sohár,