| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220377 | Tetrahedron | 2012 | 9 Pages |
Abstract
Based on 'click chemistry', the new convergent synthesis to a variety of saccharide-linked 2,6-pyridylene ethynylene 'ethynylpyridine' foldamers was developed. Ethynylpyridine 6-, 9-, and 12-meric blocks were linked with 1,7-octadiyne linker block by Sonogashira reaction, and joined with azido group-introduced glucoside, galactoside, and mannoside templates by Huisgen reaction. The resulting saccharide-linked ethynylpyridine foldamers exhibited typical circular dichroism to indicate the formation of a helical structure by intramolecular hydrogen bonds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hajime Abe, Hiroki Makida, Masahiko Inouye,