Article ID Journal Published Year Pages File Type
5220473 Tetrahedron 2011 6 Pages PDF
Abstract

A new, one-pot convenient method for the synthesis of a variety of β-phosphonomalonates by a tandem Knoevenagel-phospha-Michael reaction of phosphite esters with aryl/heteroaryl/alkyl aldehydes and malonitrile in an aqueous micellar solution of sodium stearate is described. This method offers several advantages, such as using a cheap and environmentally benign reaction media, low loadings of sodium stearate as catalyst and offers good yields.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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