Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220501 | Tetrahedron | 2011 | 8 Pages |
Abstract
A large variety of Boc-, Bz-, Ts-, and Fmoc- protected hydrazones were prepared via condensation of an equimolar amount of carbonyl-compound and the corresponding hydrazine using a ball-mill. Hydrazones were always obtained in a quantitative yield and no solvents were used at any step. In a second step, we realized the first solvent-free N-allylation and N-benzylation of these hydrazones.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pierrick Nun, Charlotte Martin, Jean Martinez, Frédéric Lamaty,