Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220550 | Tetrahedron | 2011 | 12 Pages |
Abstract
C-branched-chain sugars and nucleosides were obtained by organocatalysis from ulose derivatives. After a reduction step, the corresponding 1,3-diol was derivatized into 3â²-spiro-sulfamidates and unexpected sulfates by treatment with a Burgess reagent. Deprotection of the Boc-derivatives was carried out while preserving the cyclic sulfate. An example of ring opening of the cyclic sulfate derivative with sodium azide leading to the corresponding 3â²-C-azidoalkyl branched-chain nucleosides is given.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jérôme Lalot, Tony Tite, Anne Wadouachi, Denis Postel, Albert Nguyen Van Nhien,