Article ID Journal Published Year Pages File Type
5220553 Tetrahedron 2011 9 Pages PDF
Abstract

We describe the conception, synthesis, and characterization of a novel cyclopeptide designed for chiral recognition. The asymmetric units are built from an unnatural amino acid in the series of α-aryl-α-methyl glycine. Modifications of standard methods of peptide synthesis are described in order to improve yields and purities when applied to hindered amino acids. First set of experiments about host–guest ability of the obtained cyclopeptide is disclosed.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry