Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220553 | Tetrahedron | 2011 | 9 Pages |
Abstract
We describe the conception, synthesis, and characterization of a novel cyclopeptide designed for chiral recognition. The asymmetric units are built from an unnatural amino acid in the series of α-aryl-α-methyl glycine. Modifications of standard methods of peptide synthesis are described in order to improve yields and purities when applied to hindered amino acids. First set of experiments about host–guest ability of the obtained cyclopeptide is disclosed.
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