Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220622 | Tetrahedron | 2011 | 6 Pages |
Abstract
The synthesis of 1,6-dihydropyrrolo[2,3-g]indazole derivatives is described. The indolic ring system is constructed via a Larock palladium-catalyzed annulation using terminal and internal alkynes. Additionally, when using internal alkynes for this reaction, we found that a directing effect on regioselectivity was mediated by the ester group of alkyl 3-substituted propiolate derivatives.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Laurent Gavara, Fabrice Anizon, Pascale Moreau,