Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220623 | Tetrahedron | 2011 | 7 Pages |
Abstract
New porphyrin/4-quinolone conjugates were synthesized from the Suzuki-Miyaura coupling reaction of a β-borylated porphyrin with bromo-4-quinolones containing N-ethyl and N-d-ribofuranosyl substituents. The use of electrospray ionization tandem mass spectrometry showed important information about the fragmentation pathways of the new compounds. It was possible to distinguish between those compounds with the porphyrin moiety linked at the 6-position of the quinolone unit from their 7-substituted isomers. The new compounds showed to be good singlet oxygen generators.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ana T.P.C. Gomes, Anna C. Cunha, Maria do Rosário M. Domingues, Maria G.P.M.S. Neves, Augusto C. Tomé, Artur M.S. Silva, Fernanda da C. Santos, Maria C.B.V. Souza, Vitor F. Ferreira, José A.S. Cavaleiro,