| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220630 | Tetrahedron | 2011 | 6 Pages |
Abstract
Allyl or benzyl halides, through a Pd(0)-catalyzed reaction and under CO pressure, generate acyl-palladium/halides that, in the presence of a base and an aryl- and alkyl-acetylene, undergo nucleophilic acyl substitution giving conjugated acetylenic ketones. Diynes, resulting from alkyne/alkyne homo-coupling, were instead the main products in reactions performed without allyl or benzyl halides. Moreover, dimerization, trimerization, and cyclotrimerization reactions of acetylenes were observed in reaction carried out even without base.
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Chemistry
Organic Chemistry
Authors
Serena Perrone, Fabio Bona, Luigino Troisi,