Article ID Journal Published Year Pages File Type
5220633 Tetrahedron 2011 6 Pages PDF
Abstract

A mild copper(II)-catalyzed oxidation of 4-carboxythiazolines and 4-carboxyoxazolines to 4-carboxythiazoles and 4-carboxyoxazoles has been developed. Various substrates with alkyl or aryl substitutions at 2-position on azoline ring could be smoothly oxidized to the desired products in good to excellent yields. Moreover, the hydrolysis of the ester group could be avoided under this method.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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