| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5220636 | Tetrahedron | 2011 | 5 Pages |
Abstract
A direct and efficient approach for the preparation of pyrazolophthalazinyl spirooxindoles has been developed through one-pot three-component reaction of easily available isatin, malononitrile or cyanoacetic ester, and phthalhydrazide catalyzed by nickel chloride in polyethylene glycol 600. Desired products were obtained in high to excellent yields using a simple workup procedure.
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