Article ID Journal Published Year Pages File Type
5220650 Tetrahedron 2012 5 Pages PDF
Abstract

Ni(0)/NHC-based catalyst system can promote the amination of N-heteroaryl methyl ethers via the cleavage of normally unreactive carbon-oxygen bonds. Electron-deficient N-heteroarenes including pyridine, quinoline, isoquinoline, and quinoxaline undergo amination to afford aminopyridine and related heteroarenes, which constitute an important class of compounds.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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