Article ID Journal Published Year Pages File Type
5220725 Tetrahedron 2012 5 Pages PDF
Abstract

A novel AgOAc-catalyzed vinylogous Mannich reaction between easily prepared imines 1 derived from isatins and trimethylsilyloxyfuran 2 (TMSOF) was developed. This method provided a facile synthetic route to get access to synthetically useful quaternary 3-aminooxindole in excellent yields (94-99%) and diastereoselectivities (>99:1).

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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