Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5220766 | Tetrahedron | 2011 | 6 Pages |
Abstract
Reported herein is the isolation and structure elucidation of three highly modified peptides, actinoramides A-C (1-3), which are produced by a marine bacterium closely related to the genus Streptomyces. The planar structures of the actinoramides, which are composed of the unusual amino acids 2-amino-4-ureidobutanoic acid and 4-amino-3-hydroxy-2-methyl-5-phenylpentanoic acid, were assigned by chemical transformations and by interpretation of spectroscopic data, while the absolute configuration of these new peptides were defined by application of the advanced Marfey's and Mosher's methods.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sang-Jip Nam, Christopher A. Kauffman, Paul R. Jensen, William Fenical,